We may be already pondering things... **points downthread**

Shirt-changing isn't that important (except for Hannibal, who would be furious if his plot partner spills anything on his shirt and will be zooming off almost rudely the moment they're freed to change his shirt and properly re-tie his tie, even if it was a polite fluffy partner and not a cracky one), but nobody that's baseline human can realistically not go to the loo. With a partner of the same gender, it would be easier, especially for male pups. In any case, it would present another occasion for much juvenile crack.