Mac and Marguerite: Some contagious disease that would mean nothing four hundred years later.
Teresa: Already dead of Claymore.
Renee: Bullet. Maybe stabbing. Maybe she'll explode with rage when she gets to Flashpoint. Dinah: Supervillain. Lawton: Green Lantern (end of Secret Six. Screw the DCnU)
By sword, from magic, or too much ale. Any one of those could do it. Who knows what the writers of Merlin have planned for him. Maybe he'll join the "Killed Off, But Now I'm Back!" Club.
Gaeta: [spoilers] Executed by firing squad after a failed mutiny. [/spoilers] The Trickster: [spoilers] Stabbed through the heart by Lucifer. THANKS, BRO. Bag of dicks. >:( [/spoilers] Olivia: [spoilers] Well, aside from getting shot in the head by Walter (which was only temporary, because apparently she's Wolverine now, I DON'T EVEN KNOW), she's either missing or dead by the 2030s. William Bell is involved somehow. [/spoilers] Mac: Old age, most likely. Look, I have a pup who doesn't die in canon! MADNESS. ...and of course she's the pup I hardly ever play anymore. Er.
Looking at this list -- and at my track record with past pups (Wash, Sylar, etc) -- it's easy to see why agonistes' reaction to finding out I'd apped Bolin was, "Watch him get stabbed through the chest next season." I wouldn't even be surprised at this rate. *resigned*
Felix... well, he'd prefer to die having just saved his world again, even if only a small part of it. And with the knowledge that there are others who will take up saving-duty in his place. Including the more recent canon I ignore, the odds are pretty good for either "in secret, having been a Mysterious Figure who betrays the bad guys and only reveals himself as he's dying from their retaliation" or "of old age, a couple thousand years hence". As for how it actually will happen, looking only at Felix-as-he-is-in-Milliways... I'm not sure. Possibly he'll go into the Falloutverse again and be near one too many exploding cars.
Kain: in battle.
Fluttershy doesn't die. If you strike her down, she will become more powerful than you can possibly imagine - but you wouldn't want to do that anyway.
Cata and Sam: On the job, though for a moment there Sam thought he was going to die of Darkgate (REMEMBER THE DARKGATE, KIDS?). But someone else took the human-sacrifice hit. (And, as Cam pointed out, respawners don't mean it doesn't count, so Cata's already been shot and set on fire on a couple TF2-'verse excursions.)
Claudia: Artifact.
Apollo: N/A, as much as it can be N/A for Percyverse; it is possible for gods to fade out from lack of worship, but the dude has so many domains he's set for eternity.
Imp: Already has. Twice, in fact. Once from a ricocheting axe and once from a cart crash. Good thing Death's granddaughter likes him, eh? XD His third go-round won't be quite so dramatic.
Regulus: Won't be committing suicide by zombie lake if I have anything to say about it. OH WAIT I DO. I'm not sure how it'll play out instead, though. Quinn and I have some ideas, if we ever get to that point in gameplay.
Red: Misadventure. But not, and this is crucial, hunting party. If she gets killed by her fellow(?) humans it'll be because she's defending her friends.
And, because I feel like tossing her in: Rebecca: Artifact. Sort of. Also cancer (which, as she notes in canon, is a pretty weird sort of luck in that she lived that long). But also Artifact. AND THEN I CRIED FOREVER.
Kirk: Pointlessly, at the hands of creative team that didn't know what to do with him. Followed by an equally pointless resurrection written by Shatner in a strange if oddly entertaining series of Trek novels. He SHOULD have died in battle against the Romulans at the Tomed Incident.
Charlie: The first time was cancer. That WILL NOT happen again. I think this time it will be in an ashram in Tibet, probably from the aches and pains of life.
Knox: heart attack in his 70s
Cyborg: Some sort of alien cyberhack attach in the 22nd century. All those cyborg parts are going to let Cy live a long time and see a lot of things first.
Howard Stark: Auto accident when his son was 17. Funny that I play two pups whose fate is already known.
Ray: I don't know. I know what happens afterwards, though. Gordon: I reserve the right not to say just yet. Adrian: In a helicopter. It will be the first and only time he ever leaves one of those things without throwing up. Ellen: I have no idea. Probably bullets. Possibly wildlife. Hopefully not radiation. That's a bad way to go. Arcade: Depends how his canon plays out. He's got several very ugly possible canonical deaths. If he survives canon, who knows. Belar: Following Mom. Medic: How won't he die? Just because there's respawners in use doesn't mean the deaths don't count. Mordin: Of SPOILERS Varric: Don't know. He survives at least one main canon installment, but this is Bioware. He might wind up dead in game three for all I know. Thalestris: Javelin to the midsection during the bull-dancers' revolt. Sorry. Canon.
→ Ben Wade (almosthonorable) : bullet(s) → Gina Cowell (deadlinedriven) : old age → Kate Warner (justdidntseeit) : cancer, way on down the line (thanks to family history and the long-term residual effects of a nuclear bomb detonating in the Mojave) → Ned Stark (houseofhonor) : Ice, Ice baby sword → Raylan Givens (itwasjustified) : bullet(s)
Mia: Either a magic experiment gone wrong or old age. If she's lucky it'll be the latter.
Lucas: Oh geez you guys. Either he destroys the world and survives at the end of the game or he dies along with it. The power he obtains by pulling the majority of the seven needles is to shape the world to his liking. But it also means starting again from scratch. The last images we see of the game are horrific natural disasters before the screen fades to white and then black. However, if you move around and click at stuff, you can interact with characters in the void left behind...
...Okay, I don't actually know, because Marvel. Thor's comics history as regards death is pretty convoluted, as I understand it, and has some major differences from the movie version; I doubt the movies are going to kill him off. In Norse mythology, Thor dies at Ragnarok from wounds received while defeating the great serpent Jormungandr, but Norse mythology and the Marvel version contain a lot of very significant differences. One of those differences is a fundamentally different attitude towards fate and the role of the 'gods'. (Scare quotes not for mythology, but for comics Asgardians.)
My tentative headcanon is that there's some kind of foretelling that Thor will die at Ragnarok if he lives to see it, thus keeping the Ragnarok specter while preserving more ambiguity, but I dunno really. Anyway, the answer is definitely "in battle, being a meat-shield for other people."
River: in battle, in her early 50s or so. She's got a few decades yet.
Trowa: illness in at least moderately old age, surprising himself more than anyone.
Uzura: WHO KNOWS. She's a puppet!
Regan: illness of some sort, in old age. She doesn't live a violent-death sort of life.
Clare: GOOD QUESTION. It'll be violent somehow, because that's how Claymores roll (and the only way they can die), but she's been pretty good at surviving so far.
Yrael: Eventually fading over the eons until there isn't enough left of him to hold together. Or, if necessity catches him right, in a self-sacrificial blaze of glory on behalf of his friends and/or home who are in danger.
Sunshine: Either overwhelmed in battle and torn to pieces, or of old age.
Zelgadiss: Saving Amelia from some extremely powerful being. It will be tragic, and be used to spur the group on to fight harder and ultimately win. ^_^ Old aaage!
Ben Grimm: Of old age 6,000+ years from now thanks to Johnathan Hickman! Hank McCoy: I think he dies of old age also, ideally after seeing great strides in mutant rights. Julie Finster/84: This is hard cause she's just a kid. Slowing down or delaying an alien invasion. Beast Boy: Another one that hard cause he's just a kid. Knowing canon I'm tempted to say at the hands of Queen Bee. Mars: N/A Thalia Grace: So very close to n/a but she can die by violent means. The romantic in me says old age after Artemis releases her from her Oath but Thalia wouldn't give up an oath willingly so likely killed by a Titan or monster. Perhaps that damned manticor while protecting half-bloods and/or other hunters. Palamedes: Another that's close to n/a. I'm going to say protecting William Shakespeare and likely by Cernenous' hand while taking down the archon as well. Kate Kane: Super villain while protecting Gotham.
Castiel: In a messy blaze of glory, leaving behind a bedraggled trench coat which he will turn up to reclaim in a few months. (Because he is the Energizer Bunny of angels.)
Parker Lee: At an advanced age, but in the middle of doing something (baking cookies, weeding a garden, running for Congress). I don't think Parker ever slows down.
Luna Lovegood: Doing something improbable, I'm sure.
Mary Bennet: Just given the time period, probably from disease or an untreatable medical condition. But not for a good long while, because I want her to get to see some of those amazing 'futuristic' things.
SPOILER:Around issue 60 or so, Mark travels to the future to deal with an insane, despotic version of himself. This future-self is so out of his mind that he literally demands that Mark kill him, while trying to kill Mark. Mark ends up killing his future-self, freeing Earth from his rule, before being sent back to the current day. Ergo, Mark killed himself.
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